Adult neural stem cells

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Frontiers in cellular neuroscience. NSCs can be cultured in vitro as neurospheres. Non-invasive imaging methods, such as magnetic resonance imaging and positron emission tomography, also have the potential to revolutionize adult NSC studies in humans, but remain to be validated. Adult NSCs themselves may also contribute to the niche through autocrine and paracrine signaling Figure 4. One interesting mechanistic question is whether such plasticity in vivo involves a return to NSC state, even transiently, followed by differentiation Bar-Nur et al. Area Viewpoints References SVZ Important in the ability of a rodent mother to recognize and nurture her offspring, as it is shown that a release of prolactin in pregnancy is associated with increased SVZ neurogenesis Shingo et al. Author information Article notes Copyright and License information Disclaimer.

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Motor neurons and the sense of place.

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Yet, the latter has to be seen in perspective: Pubmed Abstract Pubmed Full Text. Regions of the postnatal brain that continue to receive new neurons may be plastic throughout life; they may not be constrained by defined critical-periods of plasticity that ends as their neuronal components mature Southwell et al. Importantly, this assay allows discrimination between neural stem and progenitor cells. Adult SGZ NSCs appear to originate from the ventral hippocampus during late gestation and then re-locate to the dorsal hippocampus Li et al. The ependymal cells and astrocytes form glial tubes used by migrating neuroblasts. Miriam and Sheldon G.

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